Human IL-6 Antibody (Monoclonal Mouse IgG1 Clone##19D6)

Cat.No.: DA013

Spcificty:
Antibody recognizes human interliukin-6 (IL-6)
Isotype:
Mouse IgG1
Source:
Cultrued in vitro under conditions free from animal derived components.
Product buffer solution:
PBS, pH 7.4, 0.09 % sodium azide (NaN3).
Shelf life and storage:
24 months from manufacturing at ≤ -20°C. 1 month, 2 to 8 °C under sterile conditions.
Description:
IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma,especially burns or other tissue damage leading to inflammation. IL-6 is relevant to many disease processes such as diabetes, atherosclerosis, depression, Alzheimer's Disease,systemic lupu serythematosus, cancer, and rheumatoid arthritis.
PARAMETERS TESTED ON EACH LOT
Product appearance:
Liquid, may turn slightly opaque during storage.
Product concentration:
5.0 mg/ml (+/- 10 %)
Immunoreactivity:
80-120 % compared to the reference sample in an ELISA test.
Purity:
≥95 %
PARAMETERS DETERMINED DURING PRODUCT DEVELOPMENT
Association rate constant (ka):
2.1×105 1/Ms
Dissociation rate constant (kd):
< 5.0×10-6 1/s
Affinity constant (kD):
<2.3×10-11M (23pM)
Determination method:
SPR analysis
Determination antigen:
Recombinant Human IL-6 (DC009)
Cross-reactivities:
Not Determined (N/D)
Epitope:
N/D
Immunoreactivity:
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Product stability:
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Pair recommendations:
CAPTURE ANTIBODY DETECTION ANTIBODYDA012 (clone#15H5) DA013(clone#19D6)Please not that pair recommendations are based on results obtained by ourlaboratory. Equally good results may be obtained using other pairs and therefore these recommendations are only indicative.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY

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