Recombinant Human Apolipoprotein A-IV/ApoA4 (C-6His) is produced by Mammalian expression system and the target gene encoding Glu21-Ser396 is expressed with a 6His tag at the C-terminus.
Apolipoprotein A-IV; Apo-AIV; ApoA-IV; Apolipoprotein A4; APOA4
AP Mol Mass:
46kDa, reducing conditions
Greater than 95% as determined by reducing SDS-PAGE.
Supplied as a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.
Reconstituted protein solution should be stored at ≤ -20°C.
Affinity purification chromatography.
Immunogen, calibrator or standard.
Apolipoprotein A4 (APOA4) is a secreted protein that belongs to the apolipoprotein A1/A4/E family. Apoa-IV is a major component of HDL and chylomicrons. APOA4 is secreted into circulation on the surface of newly synthesized chylomicron particles. APOA4 play a role in the regulation of appetite and satiety in rodent models. APOA4 involved in chylomicrons and VLDL secretion and catabolism and required for efficient activation of lipoprotein lipase by ApoC-II. In addition, APOA4 is a potent activator of lecithin-cholesterol acyltransferase in vitro.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY