ApoA4 Antigen

Cat.No.: DCA08

Derived From:
Human Cells
Description:
Recombinant Human Apolipoprotein A-IV/ApoA4 (C-6His) is produced by Mammalian expression system and the target gene encoding Glu21-Ser396 is expressed with a 6His tag at the C-terminus.
Accession:
P06727
Names(Known as):
Apolipoprotein A-IV; Apo-AIV; ApoA-IV; Apolipoprotein A4; APOA4
Quality Control:
Mol Mass:
44.44kDa
AP Mol Mass:
46kDa, reducing conditions
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Shipping:
The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Affinity purification chromatography.
Immunoreactivity:
N.A.
Application:
Immunogen, calibrator or standard.
Background:
Apolipoprotein A4 (APOA4) is a secreted protein that belongs to the apolipoprotein A1/A4/E family. Apoa-IV is a major component of HDL and chylomicrons. APOA4 is secreted into circulation on the surface of newly synthesized chylomicron particles. APOA4 play a role in the regulation of appetite and satiety in rodent models. APOA4 involved in chylomicrons and VLDL secretion and catabolism and required for efficient activation of lipoprotein lipase by ApoC-II. In addition, APOA4 is a potent activator of lecithin-cholesterol acyltransferase in vitro.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY

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