ApoH Antigen

Cat.No.: DC432

Derived From:
Human Cells
Description:
Recombinant Human Apolipoprotein H/ApoH (C-6His) is produced by Mammalian expression system and the target gene encoding Gly20-Ser345 is expressed with a 6His tag at the C-terminus.
Accession:
P02749
Names(Known as):
Beta-2-Glycoprotein 1; APC inhibitor; Activated Protein C-Binding Protein; Anticardiolipin Cofactor; Apolipoprotein H; Apo-H; Beta-2-Glycoprotein I; B2GPIBeta(2)GPI; APOH; B2G1
Quality Control:
Mol Mass:
37.29kDa
AP Mol Mass:
45-70kDa, reducing conditions
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Shipping:
The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Affinity purification chromatography.
Immunoreactivity:
N.A.
Application:
Immunogen, calibrator or standard.
Background:
Apolipoprotein H (ApoH) is a 50 kDa variably glycosylated member of the complement control superfamily of proteins. Human ApoH is a major phospholipid binding protein and an important component to measure in the assessment of anti-phospholipid syndrome. Hepatocyte-derived ApoH binds to negatively charged phospholipids . It circulates as a component of lipoprotein particles and as a lipid-free serum protein. Human ApoH is also more specific than anti-cardiolipin antibodies and its presence correlates better with thrombotic risk. Mature human ApoH shares 76% and 82% aa sequence identity with mouse and rat ApoH.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY

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