Recombinant Human Apolipoprotein H/ApoH (C-6His) is produced by Mammalian expression system and the target gene encoding Gly20-Ser345 is expressed with a 6His tag at the C-terminus.
Beta-2-Glycoprotein 1; APC inhibitor; Activated Protein C-Binding Protein; Anticardiolipin Cofactor; Apolipoprotein H; Apo-H; Beta-2-Glycoprotein I; B2GPIBeta(2)GPI; APOH; B2G1
AP Mol Mass:
45-70kDa, reducing conditions
Greater than 95% as determined by reducing SDS-PAGE.
Supplied as a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.
Reconstituted protein solution should be stored at ≤ -20°C.
Affinity purification chromatography.
Immunogen, calibrator or standard.
Apolipoprotein H (ApoH) is a 50 kDa variably glycosylated member of the complement control superfamily of proteins. Human ApoH is a major phospholipid binding protein and an important component to measure in the assessment of anti-phospholipid syndrome. Hepatocyte-derived ApoH binds to negatively charged phospholipids . It circulates as a component of lipoprotein particles and as a lipid-free serum protein. Human ApoH is also more specific than anti-cardiolipin antibodies and its presence correlates better with thrombotic risk. Mature human ApoH shares 76% and 82% aa sequence identity with mouse and rat ApoH.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY