FABP3 Antigen

Cat.No.: DC135

Derived From:
E.coli
Description:
Recombinant Human Fatty Acid-Binding Protein 3/FABP3/H-FABP (N-6His) is produced by E.coli expression system and the target gene encoding Val2-Ala133 is expressed with a 6His tag at the N-terminus.
Accession:
P05413
Names(Known as):
Fatty Acid-Binding Protein Heart; Fatty Acid-Binding Protein 3; Heart-Type Fatty Acid-Binding Protein; H-FABP; Mammary-Derived Growth Inhibitor; MDGIMuscle Fatty Acid-Binding Protein; M-FABP; FABP3; FABP11; MDGI
Quality Control:
Mol Mass:
17.02kDa
AP Mol Mass:
15kDa, reducing conditions
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μM filtered solution of PBS, pH 6.5.
Shipping:
The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Affinity purification chromatography.
Immunoreactivity:
N.A.
Application:
Immunogen, calibrator or standard.
Background:
Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-types. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. The FABP3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is also a candidate tumor suppressor gene for human breast cancer. FABP3 is a sensitive biomarker for myocardial infarction and can be detected in the blood within one to three hours of onset of pain.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY

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