HIV p24 protein Antigen

Cat.No.: DRA19

Derived From:
E.coli
Description:
Recombinant HIV p24 protein is produced by E.coli expression system and the target gene encoding Met142-Gly355 is expressed with a 6His tag at the C-terminus.
Accession:
P12493
Names(Known as):
Capsid protein p24;Human immunodeficiency virus 1;Human immunodeficiency virus type 1 p24
Quality Control:
Mol Mass:
24.6kDa
AP Mol Mass:
25kDa, reducing conditions
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μM filtered solution of PBS, pH7.4.
Shipping:
The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Affinity purification chromatography.
Immunoreactivity:
Confirmed by reaction with monoclonal antibodies specific to p24.
Application:
Immunogen, calibrator or standard.
Background:
The HIV1 p24 protein performs highly complex orchestrated tasks during the assembly,budding maturation and infection stages of the viral replication cycle. During viral assembly,the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag p24, the major capsid protein of the HIV-1 virion, has been used in clinical trials as one of the components of the HIV-1 vaccine because of the high degree of sequence conservation between different isolates. Recombinant HIV1-p24 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY

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