IGFBP3 Antigen

Cat.No.: DRA23

Derived From:
Human Cells
Description:
Recombinant Human IGFBP3 is produced by our Mammalian expression system and the target gene encoding Gly28-Lys291 is expressed with a 6His tag at the C-terminus.
Accession:
P17936
Names(Known as):
insulin-like growth factor binding protein 3; IGFBP-3
Quality Control:
Mol Mass:
29.6kDa
AP Mol Mass:
38-55kDa, reducing conditions
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μM filtered solution of 40mM NaAc, pH 4.0.
Shipping:
The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Affinity purification chromatography.
Immunoreactivity:
N.A.
Application:
Immunogen, calibrator or standard.
Background:
Human IGFBP-3 is the major binding protein of IGF where it exists in circulation as a ternary complex with the acid-labile subunit (ALS).Human IGFBP?-3 cDNA encodes a 291 amino acid (aa) precursor protein with a 27 aa signal peptide that is processed to generate the 264 aa mature protein. Human IGFBP-3 includes a cysteine-rich C-terminal domain, a highly variable central linker domain, and another N-terminal cystein-e?rich domain.IGFBP3 is the most abundant IGF binding protein in human serum and has been shown to be a growth inhibitory, apoptosis-inducing molecule. It appears to function both by cell cycle blockade and the induction of apoptosis.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY

请在下面的搜索框输入货号和批次号,我们会尽快以邮件的形式回复您