Recombinant Human SEPSECS is produced by E.coli expression system and the target gene encoding Met1-Ser501 is expressed with a 6His tag at the N-terminus.
SLA, SLA/LP autoantigen, SLA-p35, Selenocysteinyl-tRNA(Sec) synthase, Selenocysteine synthase, Liver-pancreas antigen, Soluble liver antigen, Sec synthase, UGA suppressor tRNA-associated protein.
AP Mol Mass:
58kDa, reducing conditions
Greater than 95% as determined by reducing SDS-PAGE.
Supplied as a 0.2 μM filtered solution of 20mM Tris, 300mM NaCl, 1mM DTT, 50% Glycerol, PH 8.0.
The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.
Reconstituted protein solution should be stored at ≤ -20°C.
Affinity purification chromatography.
Immunogen, calibrator or standard.
SEPSECS catalyzes the last step of sec synthesis by way of converting O-phosphoseryl-tRNA(sec) to selenocysteinyl-tRNA(sec) using selenophosphate as the selenium donor. Furthermore, SEPSECS protein is considered a specific marker of autoimmune hepatitis.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY