sST2 Antigen

Cat.No.: DCI84

Derived From:
Human Cells
Description:
Recombinant Human IL-1 Receptor-Like 1/IL-1RL1/sST2 is produced by Mammalian expression system and the target gene encoding Lys19-Phe328 is expressed with a 6His tag at the C-terminus.
Accession:
Q01638-2
Names(Known as):
Interleukin-1 receptor-like 1;Protein ST2;DER4; sST2; T1
Quality Control:
Mol Mass:
36kDa
AP Mol Mass:
50-85kDa, reducing conditions
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μM filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:
The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Affinity purification chromatography
Immunoreactivity:
Confirmed by reaction with monoclonal antibodies specific to sST2.
Application:
Immunogen, calibrator or standard.
Background:
Interleukin 1 receptor-like 1(IL1RL1) is a member of the interleukin-1 receptor family, Contains 3 Ig-like C2-type domains and 1 TIR domain. It is highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. IL1RL1 is a receptor for interleukin-33, its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 may possibly be involved in helper T-cell function. Soluble IL1RL1 also acts as a negative regulator of Th2 cytokine production, it directly implicated in the progression of cardiac disease.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY

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