TNF beta Antigen

Cat.No.: DC181

Derived From:
E.coli
Description:
Recombinant Human Tumor Necrosis Factor β/TNFβ is produced by E.coli expression system and the target gene encoding Leu35-Leu205 is expressed.
Accession:
P01374
Names(Known as):
Lymphotoxin-Alpha;LT-Alpha;TNF-Beta;Tumor Necrosis Factor Ligand Superfamily Member1;LTA;TNFB; TNFSF1
Quality Control:
Mol Mass:
18.8kDa
AP Mol Mass:
15kDa, reducing conditions
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μM filtered solution of PBS, pH 7.4.
Shipping:
The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Ion-exchange chromatography.
Immunoreactivity:
N.A.
Application:
Immunogen, calibrator or standard.
Background:
Tumor Necrosis Factor β(TNF-β) is a secreted protein belonging to the tumor necrosis factor family. TNF-β binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM in homotrimeric form, binds to TNFRSF3/LTBR in heterotrimeric form with LTB.T NF-β forms heterotrimers with lymphotoxin-beta, which anchors TNF-β to the cell surface. TNF-β mediates the inflammatory, immunostimulatory, and antiviral response, involves in the formation of second lymphoid organs during development, has a role in apoptosis. TNF-β is produced by lymphocytes and cytotoxic for a variety of tumor cells in vitro and in vivo.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY

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