Recombinant Mouse Galectin-9 (N-GST)

Cat.No.: CR41

Recombinant Mouse Galectin-9 (N-GST)
Description
Recombinant Mouse Galectin-9 is produced by our E.coli expression system and the target gene encoding Met1-Thr322 is expressed with a GST tag at the N-terminus.
Accession #:O08573-2
Known as:Galectin-9; Lgals9; Gal-9
Formulation
Supplied as a 0.2 μm filtered solution of 20mMPB,1mMEDTA,5mMp-ME,5%Trehalose,400mMNacl,ph6.5.
Quality Control
Purity:Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin:Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Storage
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.
Background
Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.

Send Message