Recombinant Human T-cell Surface Protein Tactile/CD96(C-Fc)

Cat.No.: CS52

Recombinant Human CD96 (C-Fc)
Description
Recombinant Human T-cell Surface Protein Tactile is produced by our Mammalian expression system and the target gene encoding Val22-Met503 is expressed with a Fc tag at the C-terminus.
Accession #:P40200-2
Known as:T-cell surface protein tactile; Cell surface antigen CD96; T cell-activated increased late expression protein; CD96
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Quality Control
Purity:Greater than 95% as determined by reducing SDS-PAGE.
BioActivity:Immobilized Human PVR-His(Cat#C662) at 2μg/ml (100 μl/well) can bind Human CD96-Fc(Cat#CS52) .
Endotoxin:Less than 0.1 ng/?g (1 EU/?g) as
Reconstitution
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to
Storage
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Background
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. The CD155 ligand CD96 is a member of the Ig superfamily. It's a immunoglobulin-like protein tentatively allocated to the repertoire of human NK receptors. NK cells recognize poliovirus receptor (PVR), anectins and nectin-like protein family member serve to mediate cell-cell adhesion, cell migration, with the presence of an additional receptor, CD96. CD96 promotes NK cell adhesion to target cells expressing PVR, stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells.

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