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SAM (32mM), GMP Grade(Cat. No.:GMP-S062)
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50ml
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Description
  • S-(5’-Adenosyl)-L-methionine (SAM, AdoMet) with an activating methyl group is the methyl donor for vaccinia capping enzyme (GMP-M062) and mRNA Cap 2’-O-Methyltransferase (GMP-M072) catalyzed methylation, the storage buffer formula is: 0.005M Sulfuric Acid, 10% ETOH.
  • SAM processes are strictly controlled to ensure the end products free from impurities following the Pharmaceutical Manufacturing Guidelines. We guarantee the manufacturing and quality control comply with GMP regulation for tracking each and every step of the manufacturing process, including raw material sourcing.
  • This product has passed the HALAL certification.
Quality Control
ElementStandard
AppearanceClear and transparent solution
Visible ParticlesMeet the specification
Purity≥96%
Concentration32mM±3mM
λmax UV absorption peak259nm±2nm
Endonuclease ResiduesThe degradation of substrate was ≤10%
Exonuclease ResiduesThe degradation of substrate was ≤10%
RNase ResiduesThe degradation of substrate was ≤10%
Microbial LimitTotal aerobic microbial count≤1cfu/10ml, total yeasts and molds count≤1cfu/10ml
Storage
At -20±5℃.
Components
SKUComponentsVolume
GMP-S062-01ASAM (32mM), GMP Grade0.5ml
GMP-S062-M005SAM (32mM), GMP Grade5ml
GMP-S062-M050SAM (32mM), GMP Grade50ml
Notes
SAM is unstable at pH 7–8 at 37°C and needs to be freshly prepared before the reaction starts. The amount of SAM can be calculated in advance and the 32 mM stock solution can be diluted to a working solution prior to the start of the reaction. To avoid SAM degradation, this working solution needs to be kept on ice.
Related Products
Cat. No.Product NameCat. No.Product Name
GMP-M062Vaccinia Capping System, GMP GradeGMP-E125RNase Inhibitor, GMP Grade
GMP-M072mRNA Cap 2´-O-Methyltransferase, GMP GradeGMP-E127DNase I, GMP Grade
GMP-M012E. coli Poly(A) Polymerase, GMP GradeGMP-M036Pyrophosphatase, Inorganic (yeast), GMP Grade
GMP-E121T7 RNA Polymerase,GMP GradeGMP-S023-026NTPs, GMP Grade
仅供科研或生产使用,不可直接应用于人体。
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