Recombinant Human Prostatic Acid Phosphatase/ACPP (C-6His)

Cat.No.: C420

Recombinant Human ACPP (C-6His)
Description
Recombinant Human Prostatic Acid Phosphatase is produced by our Mammalian expression system and the target gene encoding Lys33-Asp386 is expressed with a 6His tag at the C-terminus.
Accession #:AAH16344.1
Known as:Prostatic Acid Phosphatase; PAP; 5'-Nucleotidase; 5'-NT; Ecto-5'-Nucleotidase; Thiamine Monophosphatase; TMPase; ACPP
Formulation
Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5.
Quality Control
Purity:Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin:Less than 0.1 ng/?g (1 EU/?g) as determined by LAL test.
Storage
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.
Background
Prostatic Acid Phosphatase (PAP) belongs to the histidine acid phosphatase family. PAP can catalyze the hydrolysis of member of phosphate monoestyers, including phosphorylated protein. PAP can high expression in metastasized prostate cancer, moderately expression level in bone diseases, blood cell disease, and the concentration of PAP is used to monitor and assess the proession of prostate cancer. The optimum PH of PAP is from 4 to 6; its activity can be inhibited by L(+)-tartrate.
Publication
The present invention relates generally to prostatic acid phosphatase (PAP), compositions comprising the same, and methods for producing and/or purifying the same.

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