Recombinant Human Afamin/AFM (C-6His)

Cat.No.: CW88

Recombinant Human Afamin is produced by our Mammalian expression system and the target gene encoding Leu22-Asn599 is expressed with a 6His tag at the C-terminus.
Accession #:P43652
Known as: Afamin; AFM; ALB2; ALB2alpha-Alb; ALBA; ALBAalpha-albumin; ALF; Alpha-Alb; Alpha-albumin
Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
Quality Control
Purity:Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin:Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Afamin also known as Alpha -Albumin is a secreted monomeric glycoprotein of the Alb/Albumin family of molecules. AFM is known to bind and transport vitamin E family molecules, playing an important role for transporting at the blood-brain-barrier. Afamin has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. AFM also serves as an osteoclast-derived chemoattractant for preosteoblasts, providing a rational for the observation that bone formation often follows bone resorption. The importance of Afamin in transport of molecules has led to a suggested diagnostic role in various diseases, including pre-eclampsia, ovarian cancer, and both gestational and type-2 diabetes.

Send Message